Nate Tice & Charles McDonald dive into the Week 5 NFL slate with bold predictions, matchups to watch and more. The hosts get Lost in the Sauce with their three favorite games of the week, starting with Baker Mayfield and the Tampa Bay Buccaneers taking on the Seattle Seahawks, as Nate & Charles decide if the Bucs can survive their extensive injury report.
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Next, the duo dive into the Washington Commanders taking on the Los Angeles Chargers, as LA tries to bounce back from a loss to the New York Giants last week. Finally, the Kansas City Chiefs take on the Jacksonville Jaguars on Monday night, as Trevor Lawrence tries to show the Jags’ 3-1 start is for real.
Later, Nate & Charles discuss a rare Reverse Hoss Fight of the Week, as the decrepit New England Patriots run game tries to get going against a weak Buffalo Bills run D. The episode wraps with the guys’ Hail Mary bold predictions, featuring the New York Jets run game getting going and Dillon Gabriel and the Cleveland Browns getting a big upset in London.
(2:20) – Buccaneers @ Seahawks preview
(15:35) – Commanders @ Chargers preview
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(30:00) – Chiefs @ Jaguars preview
(43:25) – Reverse Hoss Fight of the Week: Patriots @ Bills
(52:05) – Hail Mary predictions
TAMPA, FLORIDA – SEPTEMBER 21: Baker Mayfield #6 of the Tampa Bay Buccaneers warms up prior to an NFL football game against the New York Jets at Raymond James Stadium on September 21, 2025 in Tampa, Florida. (Photo by Kevin Sabitus/Getty Images)
(Photo by Kevin Sabitus/Getty Images)
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